January 2020

Describe the chemical makeup of endocannabinoids. Endocannabinoids are ester, ether, and amide derivatives of long chain polyunsaturated fatty acids. Arachidonic acid is an example of a polyunsaturated fatty acid in…

Does chronic use of THC and/or CBD by individuals with MS impact cerebral glucose metabolism? The results of "The Effects of Chronic Δ-9-Tetrahydrocannabinol (THC) and Cannabidiol (CBD) use on Cerebral…

True or False? According to the results of a survey conducted by the FDA, about 90% of US adults understand that FDA-approved prescription drugs may cause harm. False. The results…

The FDA approves the language used on package inserts of prescription drugs. Does the FDA also approve the language of "direct-to -consumer" ads? Actually, no. The language, including the risk…

Does the co-administration of THC and alcohol impact serum THC levels? Yes. According to a study by Hartman in 2015, alcohol may increase THC levels. See Answer See Answer

True or False? Approximately 60% of Americans understand that the FDA approval of a drug does not necessarily mean that the drug will help most people who use it. False.…

The United States federal government classifies marijuana as a Schedule I controlled substance. Therefore, anyone transporting marijuana across state lines is committing a federal offense and, if caught, may be…

Are the pharmacokinetic parameters of orally administered THC capsules the same for males and females? The results of a single dose study, (randomized and double blind) , which involved 13…

Does liver disease impact the expression of cannabinoid receptors on non-hepatic cells? Yes. The expression of CB1 and CB2 receptors is up-regulated during the progression of liver disease. For example,…

Describe the hepatic metabolism of THC. Phase I of the metabolism of THC by the liver involves CYP 2C9/2C19/3A4. Phase I produces 11-OH-THC, 11-COOH-THC and other compounds. Phase II involves…