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Monthly Archives

January 2020

AOTD
January 31, 2020

Today’s Answer of the Day

Describe the chemical makeup of endocannabinoids. Endocannabinoids are ester, ether, and amide derivatives of long chain polyunsaturated fatty acids. Arachidonic acid is an example of a polyunsaturated fatty acid in…
AOTD
January 30, 2020

Today’s Answer of the Day

Does chronic use of THC and/or CBD by individuals with MS impact cerebral glucose metabolism? The results of "The Effects of Chronic Δ-9-Tetrahydrocannabinol (THC) and Cannabidiol (CBD) use on Cerebral…
AOTD
January 29, 2020

Today’s Answer of the Day

True or False? According to the results of a survey conducted by the FDA, about 90% of US adults understand that FDA-approved prescription drugs may cause harm. False. The results…
AOTD
January 28, 2020

Today’s Answer of the Day

The FDA approves the language used on package inserts of prescription drugs. Does the FDA also approve the language of "direct-to -consumer" ads? Actually, no. The language, including the risk…
AOTD
January 27, 2020

Today’s Answer of the Day

Does the co-administration of THC and alcohol impact serum THC levels? Yes. According to a study by Hartman in 2015, alcohol may increase THC levels. See Answer See Answer
AOTD
January 26, 2020

Today’s Answer of the Day

True or False? Approximately 60% of Americans understand that the FDA approval of a drug does not necessarily mean that the drug will help most people who use it. False.…
AOTD
January 25, 2020

Today’s Answer of the Day

The United States federal government classifies marijuana as a Schedule I controlled substance. Therefore, anyone transporting marijuana across state lines is committing a federal offense and, if caught, may be…
AOTD
January 24, 2020

Today’s Answer of the Day

Are the pharmacokinetic parameters of orally administered THC capsules the same for males and females? The results of a single dose study, (randomized and double blind) , which involved 13…
AOTD
January 23, 2020

Today’s Answer of the Day

Does liver disease impact the expression of cannabinoid receptors on non-hepatic cells? Yes. The expression of CB1 and CB2 receptors is up-regulated during the progression of liver disease. For example,…
AOTD
January 22, 2020

Today’s Answer of the Day

Describe the hepatic metabolism of THC. Phase I of the metabolism of THC by the liver involves CYP 2C9/2C19/3A4. Phase I produces 11-OH-THC, 11-COOH-THC and other compounds. Phase II involves…