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Today’s Answer of the Day

By AOTD
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In July of 2020, the FDA announced that labeling for opioid analgesics and medicine to treat opioid use disorder (OUD) must be updated. What do the updates entail?

Today’s Answer of the Day

By AOTD
Question

Do cannabinoids induce clinical remission or affect inflammation in inflammatory bowel disease patients?

Today’s Answer of the Day

By AOTD
Question

Has the FDA approved any drugs that contain a purified drug substance derived from cannabis?

Today’s Answer of the Day

By AOTD
Question

Does the Food and Drug Administration (FDA) currently certify the levels of THC contained within CBD products?

Today’s Answer of the Day

By AOTD
Question

A common adverse effect of chronic recreational marijuana use is cannabinoid hyperemesis syndrome. In fact, cannabinoid hyperemesis syndrome is a near daily diagnosis in many Canadian emergency departments. Anecdotal evidence supports the use of haloperidol to treat the symptoms of cannabinoid hyperemesis syndrome. Is haloperidol more effective than odansetron for the treatment of the nausea and vomiting associated with cannabinoid hyperemesis syndrome?

Today’s Answer of the Day

By AOTD
Question

Cannabinoid receptors have been located in the central nervous system and the peripheral nervous system, as well as on immune cells. Have cannabinoid receptors been isolated in reproductive tissues/cells?

Today’s Answer of the Day

By AOTD
Question

What are K2 and Spice?

Today’s Answer of the Day

By AOTD
Question

Respiratory depression is associated with the overdose of opioids or benzodiazepines. Is respiratory depression associated with an overdose of cannabinoids? Why or why not?

Today’s Answer of the Day

By AOTD
Question

As of January 2020, how many Americans were using marijuana-based products for medicinal purposes?

Today’s Answer of the Day

By AOTD
Question

Cannabinoids are metabolized by many of the same cytochrome P450 enzymes as warfarin, including CYP3A4, CYP2C9, and CYP2C19. THC, CBD and CBN can inhibit the CYP2C9-mediated hydroxylation of warfarin, and thus lead to an increase in INR. Do cannabinoids also affect the metabolism of heparin? Is the metabolism of direct oral anticoagulants (DOACs), including rivaroxaban, edoxaban, and apixaban, impacted by cannabinoids?