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Answer of the Day for Nov 13, 2021

By AOTD
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Sativex® (nabixomols) is an oromucosal spray with each spray of 100 microliters containing 2.7 mg THC and 2.5 mg CBD. Nabiximols is indicated as treatment for symptom improvement in adult patients with moderate to severe spasticity due to multiple sclerosis who have not responded adequately to other anti-spasticity medication and who demonstrate clinically significant improvement in spasticity related symptoms during an initial trial of therapy. This cannabinoid-based medication is intended to be used in conjunction with the patient’s other anti-spasticity medication. What is the recommended dosing schedule for nabiximols?

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Answer of the Day for Nov 12, 2021

By AOTD
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Nabilone is a synthetic cannabinoid that is similar in structure to delta-9-THC and is for oral administration. Nabilone is used for the treatment of chemotherapy-induced nausea and vomiting. What is the recommended dosage of nabilone?

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Answer of the Day for Nov 11, 2021

By AOTD
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Dronabinol is an FDA-approved synthetic form of delta-9-THC used for the treatment of anorexia associated with weight loss in adults with AIDS, and for the treatment of nausea and vomiting associated with chemotherapy in patients who have failed conventional antiemetics. What is the recommended dosage of dronabinol?

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Answer of the Day for Nov 10, 2021

By AOTD
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Did Dr. Mechoulam synthesize novel cannabinoids? If so, what is the purpose of these synthetic cannabinoids?

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Answer of the Day for Nov 9, 2021

By AOTD
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The evidence that mammalian tissues express the CB1 receptor initiated searches for mammalian-produced chemicals that can activate the CB1 receptor. Who was the first group to identify an endogenously produced chemical that binds to a cannabinoid receptor?

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Answer of the Day for Nov 8, 2021

By AOTD
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Dr. Mechoulam and his collaborators determined that some of the cannabinoids display stereoselectivity. How did the determination of stereoselectivity lead to other advancements in our understanding of cannabinoid science?

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Answer of the Day for Nov 7, 2021

By AOTD
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Other than Δ9-THC, did Dr. Mechoulam and his lab isolate other cannabinoids?

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Answer of the Day for Nov 6, 2021

By AOTD
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Who was the first to isolate Δ9-THC?

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Answer of the Day for Nov 5, 2021

By AOTD
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On November 5, 2021, Professor Raphael Mechoulam, PhD celebrates his 91st birthday. What are some of Professor Mechoulam’s accomplishements that have made him an internationally respected and honored scientist?

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Answer of the Day for Nov 4, 2021

By AOTD
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Some patients apply CBD topically. Does CBD easily penetrate the skin?

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