AOTD

Describe the hepatic metabolism of THC. Phase I of the metabolism of THC by the liver involves CYP 2C9/2C19/3A4. Phase I produces 11-OH-THC, 11-COOH-THC and other compounds. Phase II involves…

Describe the hepatic metabolism of CBD. Phase I of the metabolism of CBD by the liver involves CYP 2C9/2C19/3A4/1A2/2D6. Phase I produces 7-OH-CBD, COOH-CBD and other compounds. Phase II involves…

True or false? As of the end of 2019, more than 3.5 million people in the US are legally using medical marijuana. True. See Answer See Answer

Nabilone is a synthetic THC product. Is the half life of nabilone shorter or longer than THC? Nabilone’s elimination half-life is shorter than THC; it has been reported to be…

True or false? The plasma half-life of THC is approximately 20 to 30 hours, and the tissue half-life is also approximately 20-30 hours. False. While the plasma half-life is approximately…

It has been described that marijuana may induce psychomotor impairment, sedation, dizziness, euphoria, and disorientation. Does the co-administration of CNS depressants with marijuana impact these CNS effects? Yes. The effects…

Some clinical studies demonstrate that the inhalation of marijuana results in significant decreases in airway resistance and increases in specific airway conductance in healthy, habitual marijuana smokers shortly after smoking.…

In the immediate post-operative period, do chronic marijuana users typically require more or less rescue analgesic agents? More. Chronic marijuana users typically report higher post-operative pain scores and require more…

What percentage of marijuana users in the US use marijuana for medicinal purposes? According to a 2017 JAMA article, nearly 10% of marijuana users in the United States report using…

True or false? Cannabinoid receptors have been isolated in the hypothalamus, pituitary, ovary, endometrium, testes, AND spermatozoa. The statement is true. Research findings indicate that marijuana affects many of the…