AOTD

CBD is a negative allosteric modulator. What does that mean? A negative allosteric modulator changes the shape of the receptor and, as a result, reduces the binding ability of components…

Some producers of cannabinoid products will provide a certificate of analysis (CoA) from an independent and certified testing laboratory. What information is typically displayed on a CoA? CoAs typically indicate…

Drug screens are sometimes done in the pre-operative. Is it clinically useful to do a drug screen for the presence of cannabinoids or cannabinoid metabolites? Drug screens for the presence…

Does CBD isolate contain any other cannabinoids or terpenes? CBD isolate is CBD in its molecular form, and is typically sold as 99+% pure. Unless indicated on the label, products…

What does "broad spectrum" mean? Broad spectrum and full spectrum are not synonymous. Broad-spectrum products are processed in such a manner as to ensure that the final product does NOT…

What does "full spectrum" marijuana product mean? Full spectrum means that the product contains all of the original compounds found in the flower of the cannabis plant (cannabinoids, terpenes and…

What medical condition is most commonly cited as the reason for using medical marijuana? Chronic pain is the most commonly cited condition. In fact, according to studies and observational reports,…

Have the results of studies conducted between 2003-2017 indicated that cannabinoids are effective at treating chronic non-cancer pain? Yes. Lynch and Ware published 2 systematic reviews (SR). One SR evaluated…

Epidemiological studies indicate that as many as 15% of inflammatory bowel disease (IBD) patients may use cannabinoids to ameliorate some of their symptoms, including improvement in diarrhea, abdominal pain and…

The findings of multiple RCTs indicate that cannabinoids effectively treat chronic pain. Do cannabinoids effectively treat the chronic pain associated with fibromyalgia? No. According to a Cochrane systematic review published…