Your Dose of Cannabis Education

Your Dose of Cannabis Education

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Your Dose of Cannabis Education is based on data from the studies and reviews published in the current peer-reviewed medical journals. Whether you are a healthcare provider, patient, caregiver, an individual working in the healthcare sector, or just a curious person, you can benefit from Your Dose of Cannabis Education

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2024-12-03
What percentage of cancer patients use cannabinoids for medicinal purposes?
"Data suggest that from 20% to more than 40% of adults with cancer report cannabis use... Regarding modes of cannabis use, participants tended to rely on edibles (65%) or combusted cannabis (51%)...both qualitative and quantitative research suggest that adults with cancer use cannabis and/or cannabinoids for multisymptom management (eg, pain, nausea, vomiting, anorexia, cachexia, anxiety, depression, insomnia), cancer-directed therapy**, and for its euphoric effects." **NOTE: Cannabinoids have NOT been found to be an effective anti-neoplastic agent in humans.
Braun, Bohlke, Abrams, et al. Cannabis and Cannabinoids in Adults With Cancer: ASCO Guideline. JCO 42, 1575-1593(2024). DOI:10.1200/JCO.23.02596
2024-12-02
Desipramine is a tricyclic antidepressant that is FDA-approved for the treatment of depression. Desipramine also has off-label uses for the treatment of bulimia nervosa, irritable bowel syndrome, neuropathic pain, overactive bladder, post-herpetic neuralgia, as well as ADHD. Some patients who have been prescribed desipramine may also consume cannabinoid-based products. Does desipramine interact with cannabinoid-based products?
Yes, according to drugs.com the interaction is classified as moderate: Central nervous system depressant effects may be additively or synergistically increased, especially in elderly or debilitated patients." Sedation and impairment of attention, judgment, thinking, and psychomotor skills may increase... Cautious dosage titration may be required, particularly at treatment initiation."
https://www.drugs.com/drug-interactions/cannabis-with-desipramine-2758-0-802-0.html?professional=1 Accessed Oct 30, 2024.
2024-11-27
What is the most common mode of CBD administration? 
According to an online survey evaluating modes of CBD administration, the most common method of CBD administration was sublingual, followed by vaping, oral ingestion of capsules and liquids, smoking, edibles, and topical administration.
Corroon J, Phillips JA. A cross-sectional study of cannabidiol users. Cannabis Cannabinoid Res. 2018;3(1):152–61.
2024-11-26
Chronic pelvic pain affects up to 15% of women in the United States.  Cannabinoid receptors are expressed on reproductive tissues (including the uterus) and non-reproductive pelvic tissues. Do patients with chronic pelvic pain use cannabinoid-based products to ameliorate their symptoms?
The conclusions of a survey of 122 chronic pelvic pain female patients indicated that up to 23% report using cannabinoid-based products as an adjunct to their prescribed therapies.  The patients use a variety of formulations and doses of cannabinoid-based products, and most report daily or weekly use.  Most users report improvement in symptoms, but did acknowledge that side effects are common.
Carrubba, Aakriti R. MD; Spaulding, Aaron C. PhD; Ebbert, Jon O. MD; DeStephano, Christopher C. MD, MPH Patient-Reported Use of Medical Cannabis for Management of Chronic Pelvic Pain [12H], Obstetrics & Gynecology: May 2020 - Volume 135 - Issue - p 84S doi: 10.1097/01.AOG.0000665024.52449.e7.
2024-11-25
What percentage of US medical marijuana legal states list cancer as a qualifying condition? 
Cancer is listed as a qualifying condition in 100% of the US medical marijuana states.  Cannabinoids have been shown to ameliorate some of the symptoms associated with cancer and the side effects associated with some cancer treatments, however, cannabinoids have not been shown to be an effective anti-cancer agent in humans in randomized controlled trials.
Weiss MC, Hibbs J, McHugh TW, Buckley M, et al. A survey of breast cancer patients’ use of cannabis before, during, and after treatment. Journal of Clinical Oncology 2020 38:15_suppl, e19210-e19210

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