Your Dose of Cannabis Education

Your Dose of Cannabis Education

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Your Dose of Cannabis Education is based on data from the studies and reviews published in the current peer-reviewed medical journals. Whether you are a healthcare provider, patient, caregiver, an individual working in the healthcare sector, or just a curious person, you can benefit from Your Dose of Cannabis Education

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2025-01-20
Does the American College of Obstetricians and Gynecologists and the American Academy of Pediatrics have recommendations for the use of cannabis-based products during pregnancy?
The American College of Obstetricians and Gynecologists as well as the American Academy of Pediatrics recommend against cannabis use during pregnancy.
Sheffield SM, Kuller JA, Murphy SK, Dotters-Katz SK, Schaumberg JE. Implications of prenatal cannabis exposure on childhood neurodevelopmental outcomes: a summary of the clinical evidence. Obstet Gynecol Surv. 2024;79(10):22. doi:10.xxxx/yyyyy.
2025-01-17
Does cannabis use impact the utero-placental unit?
Yes…"maternal impacts of cannabis use may indirectly impact fetal development via increased carbon monoxide levels, increased uterine artery resistance, placental insufficiency, and decreased expression of placental immune-activating genes."
Sheffield SM, Kuller JA, Murphy SK, Dotters-Katz SK, Schaumberg JE. Implications of prenatal cannabis exposure on childhood neurodevelopmental outcomes: a summary of the clinical evidence. Obstet Gynecol Surv. 2024;79(10):22. doi:10.xxxx/yyyyy.
2025-01-16
At what point in fetal development are endocannabinoid receptors present?
"Endocannabinoid receptors are present in the embryo as early as 5 weeks’ gestation, cannabinoid receptors are involved in early synaptogenesis and neural plasticity, and the fetal neuro- developmental period is vital for long-term neurologic outcomes."
Sheffield SM, Kuller JA, Murphy SK, Dotters-Katz SK, Schaumberg JE. Implications of prenatal cannabis exposure on childhood neurodevelopmental outcomes: a summary of the clinical evidence. Obstet Gynecol Surv. 2024;79(10):22. doi:10.xxxx/yyyyy.
2025-01-15
Has the therapeutic use of dronabinol, nabilone, CBD and nabiximols in ALS been evaluated?
Very few studies have evaluated the therapeutic use of FDA-approved and/or other nationally-approved cannabinoid-based products for the treatment of ALS. According to an August 2022 publication, "only one cross-over RCT with dronabinol and one parallel RCT with nabiximols have been carried out in patients suffering from ALS. The two trials did not report any improvement in ALS scores and the pooled effect indicated an almost significant effect favouring placebo."
Bilbao, A., Spanagel, R. Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indications. BMC Med 20, 259 (2022). https://doi.org/10.1186/s12916-022-02459-1
2025-01-14
Do a significant percentage of patients with a rheumatic condition substitute medical cannabinoids for standard medical therapies?
Yes, according to a 2024 survey study published in the American College of Rheumatology's journal. The key finding of that study include: 62.5% reported substituting medical cannabis for certain medications, including NSAIDs (54.7%), opioids (48.6%), sleep aids (29.6%), muscle relaxants (25.2%), benzodiazepines (15.5%), and gabapentinoids (10.5%); the reasons given for substituting medical cannabis were fewer side effects (39%), better symptom control (27%), and fewer adverse effects (12%); and participants who substituted medical cannabis reported significant improvements in various symptoms, including pain, sleep, anxiety and joint stiffness.
Boehneke K, Scott JR, Martel M, et al. Substituting Medical Cannabis for Medications Among Patients with Rheumatic Conditions in the United States and Canada. ACR Open Rheumatology. 05 September 2024.

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