Your Dose of Cannabis Education
Your Dose of Cannabis Education
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Your Dose of Cannabis Education is based on data from the studies and reviews published in the current peer-reviewed medical journals. Whether you are a healthcare provider, patient, caregiver, an individual working in the healthcare sector, or just a curious person, you can benefit from Your Dose of Cannabis Education.
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2025-06-25
How long should the testing period of a cannabinoid-based drug be?
According to the European Pain Federation position paper on the appropriate use of cannabis-based medicines, Ňa testing period of maximum 3 months should be considered both by patients and prescribers [or recommenders], to assess treatment efficacy and safety. At the end of this testing period, long_term treatment should only be considered with significant improvement and lack of safety issuesÉ.If a satisfactory outcome is achieved, the patient should remain under close medical surveillance for the duration of cannabis_based medicine therapyÉ If the predefined treatment goals are not achieved and/or unacceptable burden of side effects occur and/or signs of abuse and misuse are observed, the specific cannabis_based medicines should be safely withdrawn and alternative options actively explored.ÓHŠuser, W, Finn, DP, Kalso, E, et al. European Pain Federation (EFIC) position paper on appropriate use of cannabis_based medicines and medical cannabis for chronic pain management. Eur J Pain.. 2018; 22: 1547Đ 1564. https://pubmed.ncbi.nlm.nih.gov/30074291/
2025-06-24
Considering the pharmacokinetics of orally consumed cannabinoid-based food products, how should the oral consumption of cannabinoids proceed?
According to Health CanadaŐs document entitled Information for Health Care Professionals: Cannabis and Cannabinoids, Ňconsumption of É oral cannabis should proceed slowly, waiting a É minimum of 30 minutes, but preferably 3 h, between bites of cannabis-based oral products (e.g. cookies, baked goods) to gauge for strength of effects or for possible overdosing.ÓInformation for Health Care Professionals Đ Cannabis (marihuana, marijuana) and the Cannabinoids Đ Dried or fresh plant and oil for administration by ingestion or other means Psychoactive agent. This document can be found at https://www.canada.ca/content/dam/hc-sc/documents/services/drugs-medication/cannabis/information-medical-practitioners/information-health-care-professionals-cannabis-cannabinoids-eng.pdf
2025-06-23
Does pretreatment with CBD prevent the transient psychotic symptoms induced by THC?
According to a study in humans, pretreatment with CBD does diminish THCŐs psychotic effects. This particular study involved 6 healthy volunteers who were given THC intravenously on two separate occasions Đ once with a placebo pretreatment and once with a CBD pretreatment.Atakan Z. Cannabis, a complex plant: different compounds and different effects on individuals. Ther Adv Psychopharmacol 2012 Dec; 2(6):241-254. doi:10.1177/2045125312457586. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736954/
2025-06-20
Has any national drug administration approved a CBD-containing product for therapeutic use in conditions other than epilepsy?
Yes. The oromucosal spray Sativex (nabiximols) is a cannabis extract that contains the principal cannabinoids delta-9-tetrahydrocannibinol (THC) and cannabidiol (CBD) in a 50:50 ratio, as well as specific minor cannabinoids and other non-cannabinoid components. Regulatory approval of Sativex has been obtained in numerous countries outside the United States for the treatment of multiple sclerosis symptoms (nerve pain, spasticity, overactive bladder, and other symptoms).GW Pharmaceuticals website. Sativex. https://www.gwpharm.com/healthcare-professionals/sativex
2025-06-19
St. John's wort is an over the counter medication used as a remedy for mild depression. Does St. John's wort interact with CBD?
Yes. St. Johns wort inhibits some of the liver enzymes that metabolize CBD. As a result, there is an increase in bioavailability of CBD, and a possible increase of adverse effects associated with CBD consumption. (Adverse effects of CBD include somnolence; decreased appetite; diarrhea; fatigue; rash; insomnia, sleep disorder, and poor quality sleep.)Brown JD, Winterstein AG. Potential Adverse Drug Events and Drug-Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use. J Clin Med. 2019;8(7):989. Published 2019 Jul 8. doi:10.3390/jcm8070989. https://pubmed.ncbi.nlm.nih.gov/31288397/
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