Your Dose of Cannabis Education

Your Dose of Cannabis Education

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Your Dose of Cannabis Education is based on data from the studies and reviews published in the current peer-reviewed medical journals. Whether you are a healthcare provider, patient, caregiver, an individual working in the healthcare sector, or just a curious person, you can benefit from Your Dose of Cannabis Education. 

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2025-10-02
Do cannabinoids modify the metabolism of theophylline?
Yes. The combination of smoked marijuana and theophylline may lead to a decrease in theophylline levels.
Jusko WJ, Gardner MJ, Mangione A, Schentag JJ, Koup JR, Vance JW (1979). Factors affecting theophylline clearances: age, tobacco, marijuana, cirrhosis, congestive heart failure, obesity, oral contraceptives, benzodiazepines, barbiturates, and ethanol. J Pharm Sci 68: 1358 - 1366.
2025-10-01
Are there any special considerations for patients who consume cannabinoid-based products and are undergoing plastic surgery?
Yes. On occasion, plastic surgeons administer medicines such as atropine and/or epinephrine during a procedure. Both of these medications can increase heart rate. Cannabinoids may potentiate the increase in heart rate.
Edalatpour A, Attaluri P, Larson JD. Medicinal and Recreational Marijuana: Review of the Literature and Recommendations for the Plastic Surgeon. Plast Reconstr Surg Glob Open. 2020 May 29;8(5):e2838. doi: 10.1097/GOX.0000000000002838. PMID: 33133899; PMCID: PMC7572176.
2025-09-30
What cardiac events have been seen in pediatric patients who consume edible recreational cannabis?
According to a retrospective analysis of the National Poison Data System data for pediatric exposures to edible cannabis products in children younger than 6 years from 2017 to 2021, involving 7043 exposures, "tachycardia was seen in 548 cases (11.4%), whereas bradycardia was seen in 68 cases (1.4%)... Hypotension, in 123 cases (2.5%), was more common than hypertension, 43 cases (0.9%)."
Tweet MS, Nemanich A, Wahl M. Pediatric Edible Cannabis Exposures and Acute Toxicity: 2017-2021. Pediatrics. 2023;151(2):e2022057761
2025-09-29
If a parturient consumes cannabis, does THC get excreted in the breastmilk?
Yes, and in fact, "THC can be found in breast milk for up to 6_days after maternal consumption, [and ]it may be concentrated up to sevenfold compared with maternal plasma in chronic consumption....The relative infant dose, the amount absorbed, has been estimated to be 2.5% (range 0.4%-8.7%) of the maternal dose."
Shah S, Schwenk ES, Sondekoppam RV, et al. ASRA Pain Medicine consensus guidelines on the management of the perioperative patient on cannabis and cannabinoids. Regional Anesthesia & Pain Medicine Published Online First: 03 January 2023. doi: 10.1136/rapm-20
2025-09-26
Some cannabinoid-based medicines are used to treat chemotherapy-induced n/v. Have cannabinoid-based medicines been shown to be effective in the treatment of post-op n/v?
The results of studies indicate that neither nabilone or intravenous THC is effective for post-op n/v. Even premedication with nabilone was ineffective at treating post-op n/v.
Tapley, P., Kellett, S. Cannabis-based medicines and the perioperative physician. Perioper Med 8, 19 (2019). https://doi.org/10.1186/s13741-019-0127-x

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