Your Dose of Cannabis Education
Your Dose of Cannabis Education
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Your Dose of Cannabis Education is based on data from the studies and reviews published in the current peer-reviewed medical journals. Whether you are a healthcare provider, patient, caregiver, an individual working in the healthcare sector, or just a curious person, you can benefit from Your Dose of Cannabis Education.
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2025-05-30
In the article entitled, "Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process," the CONSERVATIVE APPROACH was described as: "a patient may start on a 5 mg once daily dose of a CBD-predominant strain and up-titrate by 5-10 mg every 2-3 days up to 40 mg CBD per day, leveraging twice daily administration when needed. If treatment goals have not been met by 40 mg/day CBD-predominant dose, consider initiating 1 mg of THC and titrating by 1 mg once per week up to 40 mg/day of THC while keeping the same CBD dose." For which types of patients is the conservative approach recommended?
"The conservative protocol is recommended for patients who may be more sensitive to drug effects. Clinically frail patients, those with complex comorbidities, polypharmacy, and/or mental health disorders may also be appropriate for the conservative approach."Bhaskar A, Bell A, Boivin M, Briques W, Brown M, Clarke H, Cyr C, Eisenberg E, de Oliveira Silva RF, Frohlich E, Georgius P, Hogg M, Horsted TI, MacCallum CA, Muller-Vahl KR, O'Connell C, Sealey R, Seibolt M, Sihota A, Smith BK, Sulak D, Vigano A, Moulin DE. Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process. J Cannabis Res. 2021 Jul 2;3(1):22. doi: 10.1186/s42238-021-00073-1. PMID: 34215346; PMCID: PMC8252988.
2025-05-29
In today's "Dose of Cannabis Education," we will continue to discuss the ROUTINE PROTOCOL described in the article entitled, "Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process." According to the article, "If 40 mg/day CBD-predominant dose does not reach treatment goals, clinicians may consider initiating 2.5 mg of THC per day and titrate by 2.5 mg THC every 2-7 days up to 40 mg/day while maintaining the same CBD-predominant dose." What is the rationale for suggesting a large range of 2-7 days during the titration process?
"The THC titration frequency of 2-7 days is a large range to promote tailoring to the patient’s needs. Clinicians are encouraged to titrate medical cannabis to the effects desired by each patient, as opposed to a specific CBD or THC dose. During the titration phase, the total daily dose of CBD and/or THC can be divided between two to four administrations."Bhaskar A, Bell A, Boivin M, Briques W, Brown M, Clarke H, Cyr C, Eisenberg E, de Oliveira Silva RF, Frohlich E, Georgius P, Hogg M, Horsted TI, MacCallum CA, Muller-Vahl KR, O'Connell C, Sealey R, Seibolt M, Sihota A, Smith BK, Sulak D, Vigano A, Moulin DE. Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process. J Cannabis Res. 2021 Jul 2;3(1):22. doi: 10.1186/s42238-021-00073-1. PMID: 34215346; PMCID: PMC8252988.
2025-05-28
In an article entitled, "Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process," the routine protocol is recommended for most patients. The initiation of the routine protocol was described as "a patient may initiate with 5 mg twice daily (bid) of a CBD-predominant strain and up-titrate by 10 mg/day (5 mg CBD bid) every 2-3 days up to 40 mg CBD per day." What are some reasons for choosing to initiate with a CBD-predominant variety?
"A key reason for choosing to initiate with a CBD-predominant variety was to prioritize safety as CBD is highly tolerable, does not induce euphoria, and has a low risk for adverse effects. In addition, many CBD-predominant preparations contain a small percentage of THC." Bhaskar A, Bell A, Boivin M, Briques W, Brown M, Clarke H, Cyr C, Eisenberg E, de Oliveira Silva RF, Frohlich E, Georgius P, Hogg M, Horsted TI, MacCallum CA, Muller-Vahl KR, O'Connell C, Sealey R, Seibolt M, Sihota A, Smith BK, Sulak D, Vigano A, Moulin DE. Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process. J Cannabis Res. 2021 Jul 2;3(1):22. doi: 10.1186/s42238-021-00073-1. PMID: 34215346; PMCID: PMC8252988.
2025-05-27
In today's "Dose of Cannabis of Cannabis Education" we will continue to review the treatment protocols suggested in the article entitled, "Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process." This protocol is a rapid protocol where the clinician initiates the patient on a balanced THC:CBD variety. .... Click below to learn more about the protocol.
The third suggested protocol is as follows: " A rapid protocol where the clinician initiates the patient on a balanced THC:CBD variety at 2.5-5 mg of each cannabinoid once or twice daily and titrates by 2.5-5 mg of each cannabinoid every 2 to 3 days until the patient reaches his/her goals or to a maximum THC dose of 40 mg/day."Bhaskar A, Bell A, Boivin M, Briques W, Brown M, Clarke H, Cyr C, Eisenberg E, de Oliveira Silva RF, Frohlich E, Georgius P, Hogg M, Horsted TI, MacCallum CA, Muller-Vahl KR, O'Connell C, Sealey R, Seibolt M, Sihota A, Smith BK, Sulak D, Vigano A, Moulin DE. Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process. J Cannabis Res. 2021 Jul 2;3(1):22. doi: 10.1186/s42238-021-00073-1. PMID: 34215346; PMCID: PMC8252988.
2025-05-23
In today's "Dose of Cannabis of Cannabis Education" we will continue to review the treatment protocols suggested in the article entitled, "Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process." This protocol is a conservative one where the clinician initiates the patient on a CBD-predominant variety... Click below to learn more about the protocol.
The second suggested protocol is as follows: "A conservative protocol where the clinician initiates the patient on a CBD-predominant variety at a dose of 5 mg once daily and titrates the CBD-predominant dose by 10 mg every 2 to 3 days until the patient reaches their goals, or up to 40 mg/day. At a CBD-predominant dose of 40 mg/day, clinicians may consider adding THC at 1 mg/day and titrate by 1 mg every 7 days until a maximum daily dose of 40 mg/day of THC."Bhaskar A, Bell A, Boivin M, Briques W, Brown M, Clarke H, Cyr C, Eisenberg E, de Oliveira Silva RF, Frohlich E, Georgius P, Hogg M, Horsted TI, MacCallum CA, Muller-Vahl KR, O'Connell C, Sealey R, Seibolt M, Sihota A, Smith BK, Sulak D, Vigano A, Moulin DE. Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process. J Cannabis Res. 2021 Jul 2;3(1):22. doi: 10.1186/s42238-021-00073-1. PMID: 34215346; PMCID: PMC8252988.
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