Your Dose of Cannabis Education
Your Dose of Cannabis Education
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Your Dose of Cannabis Education is based on data from the studies and reviews published in the current peer-reviewed medical journals. Whether you are a healthcare provider, patient, caregiver, an individual working in the healthcare sector, or just a curious person, you can benefit from Your Dose of Cannabis Education.
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2026-02-11
Pets may gain access to and ingest prescription medications or cannabis-derived products. What is the poison control number for animals? 
The ASPCA Poison Control phone number is 1-888-426-4435. This is a national number and operates 24/7/365, but unlike the human poison hotline, consultation fees typically apply per case (often referenced around $65-$95 depending on source/plan).ASPCA.org
2026-02-10
Is continued cannabis use a contraindication to breastfeeding?
In their October 2025 Clinical Consensus No.10: Cannabis Use During Pregnancy and Lactation, The American College of Obstetricians and Gynecologists (ACOG) emphasizes that "health care professionals should advise cessation of cannabis use during pregnancy and lactation. However, continued cannabis use is not a contraindication to breastfeeding, and breastfeeding should not be discouraged." It is important to note that breastfeeding has numerous positive health effects, including decreased rates of infection, asthma, and obesity and improved intellectual development. According to the American College of Obstetrics and Gynecology, there are no medical indications for cannabis use during pregnancy or the postpartum period. ACOG. (2025). ACOG Clinical Consensus No. 10: Cannabis use during pregnancy and lactation. Obstetrics & Gynecology, 146(4), 600-611. https://doi.org/10.1097/AOG.0000000000006053
2026-02-09
CBD may inhibit the cytochrome P450 enzyme CYP2C19. Does that pose an issue for patients who take CBD with clopidogrel (Plavix)?
Yes. Clopidogrel requires hepatic CYP2C19 metabolism to convert to its active metabolite. In vitro data demonstrate that CBD (at concentrations achieved with CBD doses of 300-1,500 mg/day in humans) may significantly inhibit CYP2C19 activity. Therefore, co-administration may reduce clopidogrel's antiplatelet efficacy and increase the risk of cardiovascular events, especially in individuals with recent coronary stent placement. Clinicians should consider monitoring for signs of reduced clopidogrel activity, such as recurrent angina, thrombosis, or stent occlusion or consider alternative antiplatelet agents which are not dependent on CYP2C19 for bioactivation. Brown, J. D., & Winterstein, A. G. (2019). Potential adverse drug events and drug-drug interactions with medical and consumer cannabidiol (CBD) use. Journal of Clinical Medicine, 8(7), 989. https://doi.org/10.3390/jcm8070989
Greger, J., Bates, V., Mechtler, L., & Gengo, F. (2020). A review of cannabis and interactions with anticoagulant and antiplatelet agents. Journal of Clinical Pharmacology, 60(4), 432-438. https://doi.org/10.1002/jcph.1557
Jiang, R., Yamaori, S., Takeda, S., Yamamoto, I., & Watanabe, K. (2013). Cannabidiol is a potent inhibitor of the catalytic activity of cytochrome P450 2C19. Drug Metabolism and Pharmacokinetics, 28(4), 332-338. https://doi.org/10.2133/dmpk.DMPK-12-RG-129
2026-02-06
Does cannabis impact the health of the placenta?
Cannabis use during pregnancy may negatively impact the health of the placenta, as cannabinoids may alter uterine/placental blood flow. There's an increase in placental resistance and a reduction placental circulation. El Marroun, H., Tiemeier, H., Steegers, E. A., et al. (2010). A prospective study on intrauterine cannabis exposure and fetal blood flow. Early Human Development, 86(4), 231-236. https://doi.org/10.1016/j.earlhumdev.2010.03.001. and Tortoriello, G., Morris, C. V., Alpar, A., et al. (2014). Miswiring the brain: _9-tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin-2 degradation pathway. EMBO Journal, 33(7), 668-685. https://doi.org/10.1002/embj.201386035
2026-02-05
What are the typical signs and symptoms of pediatric intoxication?
"Symptoms are usually nonspecific and include manifestations such as central nervous system depression (lethargy, coma), confusion, agitation, and ataxia. Nausea and vomiting, conjunctival hyperemia, mydriasis, tremors, speech difficulties, and behavioral disturbances are common. In episodes of severe intoxication, bradycardia, hypotension, convulsions, and respiratory depression have been reported, and may require orotracheal intubation." (Fradera) Although respiratory depression is not typical in adults, it may be present in pediatric patients.Fradera, A. S., Campos, L. S., Profumo, A. D., et al. (2024). Accidental cannabis intoxication with an unexpected outcome. Emergencia Pediatricas, 3(2), 91-93.
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